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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNI3K
All Species:
13.33
Human Site:
Y354
Identified Species:
29.33
UniProt:
Q59H18
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q59H18
NP_001106279.1
936
104179
Y354
G
H
H
D
I
V
K
Y
L
L
Q
S
D
L
E
Chimpanzee
Pan troglodytes
XP_513493
949
105567
Y367
G
H
H
D
I
V
K
Y
L
L
Q
S
D
L
E
Rhesus Macaque
Macaca mulatta
XP_001097254
949
105560
Y367
G
H
H
D
I
V
K
Y
L
L
Q
S
D
L
E
Dog
Lupus familis
XP_537112
1087
119299
Y522
G
H
H
D
I
V
K
Y
L
L
Q
S
D
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5GIG6
834
92569
E287
G
N
F
E
V
A
K
E
I
V
H
V
T
G
T
Rat
Rattus norvegicus
Q7TQP6
835
92713
E288
G
N
F
E
V
A
K
E
I
V
Q
V
T
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339957
835
92821
E288
G
K
F
E
A
V
K
E
I
I
Q
L
S
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021182
850
93167
K303
S
G
R
L
D
I
V
K
S
I
L
D
S
S
P
Sea Urchin
Strong. purpuratus
XP_782227
862
95496
D315
A
C
Y
T
G
R
L
D
I
V
K
S
L
I
T
Poplar Tree
Populus trichocarpa
XP_002336079
539
60951
Maize
Zea mays
NP_001152032
543
61643
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.5
80.1
N.A.
80.7
81.3
N.A.
N.A.
N.A.
N.A.
75.7
N.A.
N.A.
N.A.
36.7
51.1
Protein Similarity:
100
98.3
97.2
82.6
N.A.
84.4
85.3
N.A.
N.A.
N.A.
N.A.
83.7
N.A.
N.A.
N.A.
55
65.6
P-Site Identity:
100
100
100
93.3
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
46.6
53.3
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
13.3
40
Percent
Protein Identity:
23.6
22.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.2
36.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
0
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
19
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
37
10
0
0
10
0
0
0
10
37
0
0
% D
% Glu:
0
0
0
28
0
0
0
28
0
0
0
0
0
0
37
% E
% Phe:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
64
10
0
0
10
0
0
0
0
0
0
0
0
28
0
% G
% His:
0
37
37
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
37
10
0
0
37
19
0
0
0
10
0
% I
% Lys:
0
10
0
0
0
0
64
10
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
10
0
37
37
10
10
10
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
55
0
0
0
0
% Q
% Arg:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
10
0
0
46
19
19
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
19
0
37
% T
% Val:
0
0
0
0
19
46
10
0
0
28
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _